USP6 activation in nodular fasciitis by promoter-swapping gene fusions

Nodular Fasciitis

odular fasciitis, also known as infiltrative or pseudosarcomatous fasciitis, is a benign soft tissue tumor of fibroblastic/myofibroblastic differentiation that was first described in 1955 by Konwaler et al.1 The lesion often comes to clinical attention when a patient presents with a rapidly growing, occasionally painful, palpable soft tissue mass.2,3 Although benign and self-limited, nodular fa...

[Nodular fasciitis].

Maxillary sinus nodular fasciitis.

Nodular fasciitis is a rare and benign inflammatory condition; however, it can be misdiagnosed as a malignant lesion. We report a unique case of nodular fasciitis arising from the maxillary sinus in a 2-year-old child. Our English literature review (PubMed search), revealed a total of 3 cases published as nodular fasciitis in the para-nasal sinuses, each with a different management approach.

Nodular fasciitis induced by epidural injection.

Nodular fasciitis is a well established clinical entity of unknown pathogenesis. A traumatic aetiology is postulated yet specific examples are not documented. We present a case directly attributable to an epidural injection.

Post-aural Nodular Fasciitis.

Nodular fasciitis is a rare benign lesion. Here we report a case of post-auricular nodular fasciitis, which was misdiagnosed by fine-needle aspiration cytology (FNAC) as pleomorphic adenoma. An 18-year-old male presented at Al-Nahdha Hospital, physical examination revealed a right post aural firm immobile mass. Radiology suggested the presence of a hypo-dense to iso-dense subcutaneous mass. The...